Prospective Comparison of Cold Polypectomy and Conventional Polypectomy for Small Colorectal Polyps in Patients Taking Antithrombotic Agents

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01553565

Enrollment

160

Registered

2012-03-14

Start date

2012-03-31

Completion date

2012-12-31

Last updated

2014-08-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal Polyps

Keywords

10 mm in diameter, antithrombotic agents

Brief summary

1. Background: The ideal method to remove small colorectal polyps in patients who are taking antithrombotic agents is unknown. 2. Aim: The aim of this study is to evaluate postpolypectomy bleeding and the complete retrieval rate after the removal by colon snare transection without electrocautery for small polyps in patients who are taking antithrombotic agents. 3. Design: A prospective, consecutive study. 4. Setting: Municipal hospital outpatients. 5. Interventions: Polypectomy by cold snare technique (Cold polypectomy) was performed for colorectal polyps up to 10 mm in diameter in patients who continue to take antithrombotic agents. The primary outcome measure was bleeding within two weeks after polypectomy. Secondary outcome measure was the complete retrieval rate of colorectal polyps based on the pathological examination.

Interventions

PROCEDURECold polypectomy

All colorectal polyps up to 10 mm found except for tiny hyperplastic polyps in the rectum and distal sigmoid colon are removed. The technique is cold resection of the polyp without tenting and then suction of the transected polyp into a trap followed by submission to histopathological evaluation.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

20 Years to 90 Years

Healthy volunteers

Inclusion criteria

* Patients with colorectal polyps up to 10 mm in diameter. The patients continue to take antithrombotic agents.

Exclusion criteria

* patients are less than 20 years old, * pregnant, * American Society of Anesthesiologists class III and IV, * overweight (body weight \> 100 kg), or * allergic to propofol used or its components (soybeans or eggs), * with previous colorectal surgical resection.

Design outcomes

Primary

Measure	Time frame	Description
Postpolypectomy bleeding	2 weeks	Bleeding within two weeks after polypectomy

Secondary

Measure	Time frame	Description
Complete retrieval rate of colorectal polyps	2 weeks	The complete retrieval rate of colorectal polyps based on the pathological examination.

Countries

Japan

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026