Arthritis, Rheumatoid
Conditions
Keywords
exercise programme
Brief summary
The purpose of this study is to compare the effectiveness of a supervised high-intensity exercise programme followed by an unsupervised exercise programme to an unsupervised exercise programme in patients with Rheumatoid Arthritis.
Detailed description
Patients with Rheumatoid Arthritis are in general less fit and more at risk of comorbidities such as cardiovascular events compared with healthy age-matched controls. Studies indicates that patients with Rheumatoid Arthritis have a lower level of physical activity than the general population and a low proportion of patients with Rheumatoid Arthritis exercises. Regular exercise with moderate to high intensity level of intensity has proven to be effective in reducing the cardiovascular risk by improving cardiovascular fitness and to increase muscle strength. Therefore, it is of interest to investigate if supervised exercise programme makes a difference making patients with Rheumatoid Arthritis participate in exercise.
Interventions
OTHERSupervised high-intensity exercise programme
Six-weeks supervised high-intensity muscle strength training and physical fitness with training sessions twice a week followed by 6-weeks unsupervised high-intensity exercise programme.
OTHERExercise programme
Supervised exercise programme
Sponsors
Aarhus University Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* diagnosed with Rheumatoid Arthritis within the last three years at Aarhus University Hospital according to the 1987 revised ACR criteria or the 2009 ACR/EULAR criteria * must be able to sit on an exercise bike * must be able to participate in 6-weeks exercise programme with training sessions twice a week at Aarhus University Hospital * must be able to speak and understand danish
Exclusion criteria
* high disease activity assessed by DAS28-CRP * Myocardial Infarction within the last six months * Angina Pectoris * treated with beta-blocker * severe high blood pressure * severe lung disease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in muscle strength (kg) | Muscle strength is measured at baseline and follow-up. The outcome is change in muscle strength in 12 weeks from baseline to follow-up. |
Secondary
| Measure | Time frame |
|---|---|
| Change in cardiovascular fitness | Cardiovascular fitness is measured at baseline and follow-up. The outcome is change in cardiovascular fitness in 12 weeks from baseline to follow-up. |
Countries
Denmark
Outcome results
None listed