Studies of Pancreatic Islet Mass by Positron Emission Tomography (PET)

Open Study to Investigate Pancreatic Islet Mass by Positron Emission Tomography Using the Tracer [11C]5-hydroxytryptophane

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01552811

Enrollment

Registered

2012-03-13

Start date

2012-03-31

Completion date

2013-03-31

Last updated

2014-02-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 1 Diabetes

Brief summary

This study investigates the hypothesis that differences in beta-cell mass in patients with diabetes and healthy individuals can be monitored by the positron emission tomography (PET) tracer \[11C\]5-hydroxytryptophane.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* Adult patients with type 1 diabetes * Adult, healthy controls

Exclusion criteria

* Pregnancy * Impaired renal function

Design outcomes

Primary

Measure	Time frame
Difference in pancreatic uptake of % injected dose (ID) [11]5-hydroxy tryptophan between healthy volunteers and patients with long-standing type 1 diabetes	To be measured at Positron emission tomography investigation for all study persons.

Countries

Sweden

Outcome results