Evaluation of an Apple Juice Drink With POs-Ca

Development and Evaluation of a Low Erosive Apple Juice Drink With Phosphoryl Oligosaccharides of Calcium (POs-Ca)

Status

Completed

Phases

Early Phase 1

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01552252

Enrollment

Registered

2012-03-13

Start date

2010-03-31

Completion date

2012-03-31

Last updated

2012-03-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Food Preferences

Keywords

POs-Ca, calcium additives, drink

Brief summary

The null hypothesis tested was that there are no differences in the taste palatability of the apple juices before and after adding POs-Ca.

Interventions

DIETARY_SUPPLEMENTapple juice

unaltered(0% POs-Ca) commercially available apple juice

DIETARY_SUPPLEMENTapple juice with 0.5% POs-Ca

Phosphoryl Oligosaccharides of Calcium (POs-Ca) in the form of powder was added at concentrations of 0.5% by weight to a commercially available apple juice

DIETARY_SUPPLEMENTapple juice with 1% POs-Ca

Phosphoryl Oligosaccharides of Calcium (POs-Ca) in the form of powder was added at concentrations of 1% by weight to a commercially available apple juice

DIETARY_SUPPLEMENTapple juice with 1.5% POs-Ca

Phosphoryl Oligosaccharides of Calcium (POs-Ca) in the form of powder was added at concentrations of 1.5% by weight to a commercially available apple juice

DIETARY_SUPPLEMENTapple juice with 2% POs-Ca

Phosphoryl Oligosaccharides of Calcium (POs-Ca) in the form of powder was added at concentrations of 2% by weight to a commercially available apple juice

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

SUPPORTIVE_CARE

Masking

TRIPLE (Subject, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to 25 Years

Healthy volunteers

Yes

Inclusion criteria

* healthy adult subjects * No eating or drinking within 30 minutes before the start time of the trials * No tooth brushing within 30 minutes before the start time of the trials

Exclusion criteria

* apple hypersensibility

Design outcomes

Primary

Measure	Time frame	Description
Visual Analogue Scale of taste palatability	At time when the subjects have finished drinking, an expected average of 10 minutes	Tasters were first asked to drink the unaltered (0% POs-Ca) juice, to get familiar with the taste. After that they drank each of the 5 juices in a random order, and evaluated the taste by marking an analogue scale ranging from 0 to 100 which was printed horizontally on a sheet of paper.

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026