Early Detection of Neonatal Shock

Early Detection of Shock in Critically Ill Newborn Infants. The Impact of Advanced Hemodynamic Monitoring

Status

Terminated

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01550198

Acronym

Edscini

Enrollment

Registered

2012-03-09

Start date

2013-05-31

Completion date

2022-07-31

Last updated

2023-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Impact of Advanced Hemodynamic Monitoring

Keywords

newborn, shock, hemodynamics, cardiac output, blood pressure

Brief summary

The purpose of this study is to evaluate the hypothesis that advanced hemodynamic monitoring results in an earlier detection of circulatory failure in newborn infants

Interventions

DEVICEAdvanced hemodynamic monitoring

Comprehensive advanced hemodynamic monitoring

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* Birth weight \>700 grams * Arterial catheter in place * Central venous catheter in place * Informed consent from parents/legal representatives

Exclusion criteria

* Life-threatening congenital defects * Congenital heart defects, except patent ductus arteriosus and patent foramen ovale

Design outcomes

Primary

Measure	Time frame
Cardiac output assessed by transpulmonary ultrasound dilution and simultaneously clinically estimated cardiac output	2 years

Countries

Netherlands

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026