Taste, Non-esterified Fatty Acids
Conditions
Keywords
taste, fat, threshold, sensitivity, human
Brief summary
This study seeks to determine if non-esterified fatty acid (NEFA) taste detection thresholds change with repeated testing. Threshold testing for NEFA taste has been reported by a number of laboratories, including our own; however, these studies have reported data for only one testing occasion. The investigators seek to conduct repeated testing to measure the test-retest reliability of these methods. The investigators believe that with repeated exposure to NEFA, a person's sensitivity increases. The investigators are also testing the efficiency of testing by two methods (forced-choice ascending trial versus staircase). Additionally, the association between taste responses, diet and BMI will be explored.
Interventions
None listed
Sponsors
Purdue University
Study design
Observational model
CASE_CROSSOVER
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 55 Years
Healthy volunteers
Yes
Inclusion criteria
* 18-55 years old * in good health * available for three months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Non-esterified fatty acid detection thresholds in humans | 6 months |
| BMI | Baseline |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Habitual fat intake | Baseline | Block Rapid Dietary Fat Screener will be used as well as the ASA-24. |
| testing method | 6 months | Comparison of time to maximum sensitivity by participants based on forced-choice versus staircase stimulus presentation techniques. |
| hunger | each visit | Visual analog scale |
Countries
United States
Outcome results
None listed