Ventilator-associated Pneumonia (VAP) and Humidification System

Prospective Analysis of the Incidence of Ventilator-associated Pneumonia Related to the Humidification System: Heat and Moisture Exchanger Versus Heated Humidification

Status

UNKNOWN

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01546974

Enrollment

306

Registered

2012-03-07

Start date

2011-11-30

Completion date

2014-02-28

Last updated

2012-03-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ventilator-associated Pneumonia

Keywords

Mechanical Ventilation, Humidification system, Patients submitted to mechanical ventilation for at least 48 hours

Brief summary

The purpose of this study is to determine which humidification system is more effective in preventing pneumonia in mechanically ventilated patients. The study will compare a heat and moisture exchanger versus heated humidification.

Interventions

DEVICEHME filter Twin Star 55, Drager Medical, Germany

DEVICEHeated humidification

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Patients expected to require mechanical ventilation for at least 48 hours

Exclusion criteria

* Patients \< 18 yo and pregnant

Design outcomes

Primary

Measure	Time frame
VAP incidence	—

Secondary

Measure	Time frame
Duration of mechanical ventilation	—

Countries

Brazil

Contacts

Primary ContactJOSE R AZEVEDO, MD

jrazevedo@elo.com.br55 98 32168110

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026