From Acute to Chronic Postoperative Pain in Patients for Elective Cholecystectomy. Immunological Tests

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01546480

Enrollment

Registered

2012-03-07

Start date

2011-11-30

Completion date

2014-02-28

Last updated

2014-06-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain

Keywords

Chronic postoperative pain, Postcholecystectomy pain, Inflammation, Interleukines

Brief summary

Chronic Pain after Cholecystectomy is a well known problem. One theory is that it is due to persisting inflammation. The purpose of the study is to measure inflammatory factors in cerebrospinal fluid and blod at patients 12 months after the operation. DNA-samples are collected to examine genetical factors, important for perception of pain, and the development of chronic pain.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

Group 1: Inclusion Criteria: * Unexplained abdominal pain 12 months after elective cholecystectomy

Exclusion criteria

* Immunosuppressive treatment (NSAID excepted) * Anticoagulant treatment Group 2: Inclusion Criteria: * No pain 12 months after elective cholecystectomy

Design outcomes

Primary

Measure	Time frame	Description
Spinal interleukine levels	12 months	12 months after surgery

Secondary

Measure	Time frame	Description
Blood interleukine levels	12 Months	—
spinal enzyme levels	12 months	12 months after surgery
Blood enzyme levels	12 months	12 months after surgery

Countries

Denmark

Outcome results