Chronic Stress
Conditions
Keywords
milk protein, probiotics, stress, cortisol, heart beat
Brief summary
The study aims to investigate the role of dietary factors in chronically stressed subjects. Previous studies have shown that milk proteins, B vitamins and probiotics may influence on subjective well-being in stressed subjects.
Interventions
DIETARY_SUPPLEMENTYogurt-like snacks
twice a day 120 g for four weeks
Sponsors
SalWe Ltd.
University of Helsinki
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
* STAI points 40-65 * BMI 18-30 kg/m2 * healthy
Exclusion criteria
* Gastrointestinal disease, diabetes or any other significant major medical morbidity * milk allergy * smoking * excess use of alcohol * pregnancy and breast feeding * waist circumference males \>102 cm, females \>88 cm * no medication or dietary supplements influencing measured responses
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Subjective well-being | baseline and 4 weeks | Change in stress and mood states measured by State-trait anxiety inventory (STAI) and modified Profile of Mood States (POMS) at baseline and after 4 wk intervention |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Physiological measurements | baseline and 4 weeks | Change in salivary cortisol, blood pressure, heart beat variability, sleep and inflammatory markers. |
Countries
Finland
Outcome results
None listed