Prevention Post Operative Nausea Vomiting in Ambulatory Gynecologic Laparoscopy

Status

Completed

Phases

Phase 2

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01543945

Enrollment

340

Registered

2012-03-05

Start date

2008-03-31

Completion date

Unknown

Last updated

2012-07-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Nausea and Vomiting

Keywords

Postoperative Nausea and Vomiting, Ambulatory, Gynecologic laparoscopy, Incidence of postoperative nausea and vomiting.

Brief summary

The purpose of this study is to compare the incidence of Postoperative nausea and vomiting between the intervention group who received multimodal antiemetic management and the control group who did not get this protocol.

Interventions

DRUGDexamethasone

4 mg iv before induction for high and extremely high risk

DRUGOndansetron

4 mg iv before ended surgery 30 min

DRUGDimenhydrinate

1 mg/kg iv before ended surgery 30 min

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 45 Years

Healthy volunteers

Inclusion criteria

* Ambulatory gynecologic laparoscopy * Age 18-45 years * ASA class 1-2

Exclusion criteria

* The patients who take opioid, steroid, pyschotics or antiemetic drug within 24 hours before surgery * History of antiemetic, anesthetic and analgesic drugs allergy * Pregnancy or breast feeding * Body mass index \>34 kg/square metre

Design outcomes

Primary

Measure	Time frame
Incidence of PONV in ambulatory gynecologic laparoscopy	four year

Countries

Thailand

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026