Effects of Exercise on sRAGE Levels and Cardiometabolic Risk Factors

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01542775

Enrollment

Registered

2012-03-02

Start date

2010-01-31

Completion date

Unknown

Last updated

2012-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 2 Diabetes

Brief summary

The purpose of this study is to examine the effects of exercise on diverse cardiometabolic risk factors and indicators of atherosclerosis in patients with type 2 diabetes mellitus (T2DM).

Interventions

BEHAVIORALAerobic Exercise Group

12 weeks Aerobic exercise

BEHAVIORALControl Group

maintaining usual activities

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 85 Years

Healthy volunteers

Yes

Inclusion criteria

* type 2 diabetes * stable body weight * sedentary lifestyle

Exclusion criteria

* smoked cigarettes * cardiovascular disease * chronic kidney * chronic liver disease * pregnant or breastfeeding * any other major illness

Design outcomes

Primary

Measure	Time frame
change from baseline in soluble receptor for advanced glycation endproducts (sRAGE) after 12 weeks of aerobic exercise	12 weeks

Secondary

Measure	Time frame	Description
biochemical parameters	12 weeks	HbA1c, apolipoprotein B, free fatty acid
energy expenditure	12 weeks	activity energy expenditure, total energy expenditure
anthropometric parameters	12 weeks	body weight, waist circumference, body fat percentage, visceral fat area

Countries

South Korea

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026