Postoperative Pain
Conditions
Keywords
magnesium sulpahate, postoperative analgesia
Brief summary
intraperitoneal nebulisation with magnesuim sulphate will reduce post operative pain and analgesic consumption in postoperative period following laparoscopic cholecystectomy.
Detailed description
Sixty patients undergoing laparoscopic cholecystectomy belonging to American Society of Anaesthesiologist (I-II) of age 18-65 yrs will be enrolled.Group one (n=30) will receive 1.5 gm magnesium sulphate diluted in 3ml of normal saline and group 2 (n=30) will receive 5 ml of NS.
Interventions
DRUGintraperitoneal nebulisation of magnesium sulphate
intraperitoneal nebulisation of 1.5 gm of magnesium sulphate with 2 ml of normal saline
Sponsors
B.P. Koirala Institute of Health Sciences
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Caregiver, Investigator)
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
ASA I-II \-
Exclusion criteria
history of \-
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| number of analgesic request | 24 hour | time to first analgesic request is taken as duration of effective analgesia number of analgesic request in first 24 hours were also counted |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| VAS score | first complaint of pain, 6 hrs, 12 hrs, 24 hrs | Visual analogue scale is a linear 10cm scale with 0 corresponding to no pain and 10 to worst pain ever |
| nausea and vomiting | 24 hrs | — |
| respiratory rate | 24 hrs | — |
| sedation | 24hrs | — |
Countries
Nepal
Contacts
Primary ContactSujata Niroula, MD
Backup Contactkrishna Pokharel, MD
Outcome results
None listed