Effectiveness of Aspirin in Compare With Heparin Plus Aspirin in Recurrent Pregnancy Loss Treatment

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01542411

Enrollment

520

Registered

2012-03-02

Start date

2008-04-30

Completion date

Unknown

Last updated

2012-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Recurrent Pregnancy Loss

Brief summary

This study evaluated the effect of anticoagulant treatment on the live-birth rate in women with a history of at least two continuous unexplained miscarriages or thrombophilia. It also compared two methods of treatment with aspirin and aspirin plus heparin.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

FEMALE

Age

19 Years to 35 Years

Healthy volunteers

Yes

Inclusion criteria

* unexplained recurrent miscarriage, * women had previous venous or arterial thromboembolism or who were heterozygous or homozygous for mutations for FV Leiden G1691A, prothrombin gene G20210A (FII G20210A), and methyltetrahydrofolate reductase C677T (MTHFR C677T)

Exclusion criteria

* abnormal karyotypes of both partners, * uterine and cervical anatomical disorders on pelvic ultrasonography or hysteroscopy, * abnormal ovaries and abnormal endocrine tests.

Countries

Iran

Outcome results