Evaluating the Patient-Ventilator Synchrony During Mechanical Ventilation in Patients With Acute Lung Injury

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01541514

Enrollment

Registered

2012-03-01

Start date

2011-07-31

Completion date

2013-12-31

Last updated

2014-12-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mechanically Ventilated ICU Patients

Brief summary

The overall purpose to the study is to prospectively study how often patients with and without acute lung injury (ALI) have patient-ventilator asynchrony demonstrated as stacked breaths. The investigators seek to describe the quantity of stacked breaths by continuously recording flow, volume, and pressure waveforms routinely displayed on the vent. The investigators also seek to describe how primary ICU teams manage asynchrony documenting interventions of sedation or vent manipulation and what modality is most successful.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

age \> 18 years intubated and mechanically ventilated diagnosed with acute lung injury (ALI) or requiring mechanical ventilation for reasons other than ALI

Exclusion criteria

neurological deficits (acute or chronic) that prevent effective diaphragm activity. * Neuromuscular disease affecting the diaphragm * Neuromuscular blockade

Design outcomes

Primary

Measure	Time frame	Description
double stacks	number per minute over 5 minutes	ventilator waveform recording

Secondary

Measure	Time frame	Description
level of sedation	baseline	Richmond Agitation Sedation Score
mode of ventilation	30min	ventilator adjustment

Countries

United States

Outcome results