Pakistan Flocculent Health Outcome Study

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01538953

Enrollment

8949

Registered

2012-02-27

Start date

2003-03-31

Completion date

2004-01-31

Last updated

2012-02-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diarrhea

Keywords

diarrhea, handwashing, point-of-use water treatment, diarrhea longitudinal prevalence

Brief summary

This study is designed to evaluate the effect of different methods of drinking water treatment on the occurrence of diarrhea among children living in squatter settlements in Karachi, Pakistan, and the marginal benefit of adding handwashing to water treatment. 260 households will receive a new product which combines flocculation with chlorination to produce clearer, less chemically contaminated drinking water. 260 households will receive dilute sodium hypochlorite, i.e. bleach to treat their water. 260 households will receive soap and encouraged to wash their hands regularly. 260 households will receive both soap and the combination flocculation/chlorination water treatment. 260 households will continue their standard water treatment and handwashing practices. The households will be visited each week for 9 months, and the episodes of diarrhea from each child in the household recorded. The rate of diarrhea between the groups will be compared. At the end of 9 months, households who were part of the standard habits and practice group will receive a water storage vessel and disinfectant.

Interventions

OTHERhandwashing

participants received weekly in-home handwashing promotion and soap as needed

OTHERflocculent-disinfectant for water treatment

participants received a supply of flocculent-disinfectant product for water treatment and instruction in how to use it

OTHERwater treatment with sodium hypochlorite

participants received a supply of dilute sodium hypochlorite and instruction to treat drinking water with it

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

NONE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Yes

Inclusion criteria

* households in study neighborhoods * contain a child \< 5 years old * have access to water for handwashing

Exclusion criteria

* participated in handwashing or drinking water treatment programs with HOPE previously

Design outcomes

Primary

Measure	Time frame
diarrhea longitudinal prevalence	—

Countries

Pakistan

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 25, 2026