Perinatal Outcome After Premature Rupture of Membranes

Perinatal Outcomes According to Amniotic Fluid Indez After Premature Rupture of Membranes. A Prospective Cohort Study.

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01538030

Enrollment

Registered

2012-02-23

Start date

2012-05-31

Completion date

2012-08-31

Last updated

2012-08-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fetal Membranes, Premature Rupture

Keywords

Fetal membranes, premature rupture, Cesarean section, Perinatal mortality, Neonatal sepsis, Amniotic Fluid Volume

Brief summary

Premature rupture of membranes is an important cause of neonatal morbidity and mortality, mainly because of the complications associated with this pathology (oligohydramnios, cord compression or prolapse, infection). When rupture of the membranes occur the risk of cord compression increases but there is little evidence regarding this complication and amniotic fluid volume. The investigator's focus are the perinatal outcomes according to amniotic fluid volume (\< 5 or \>5).

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

FEMALE

Healthy volunteers

Inclusion criteria

* Gestational age between 24-34 weeks. * Confirmed diagnosis of premature rupture of membranes.

Exclusion criteria

* Twin pregnancies. * Obstetric pathologies that require immediate termination of pregnancy (severe preeclampsia, abruptio placenta, cord prolapse). * Termination of pregnancy (whatever the reason) before complete corticoid treatment. * Incomplete recollection of all data required for analysis.

Design outcomes

Primary

Measure	Time frame	Description
Cesarean section rate	5 months	Number of cases in each cohort that were interrupted by cesarean section due to fetal distress (evidence of cord dystocia).

Secondary

Measure	Time frame	Description
Perinatal mortality	5 months	Number of perinatal deaths (ante, peri and postpartum until 28 days postpartum)in each cohort.
Neonatal sepsis	5 months	Number of cases of neonates diagnosed with sepsis in each cohort.

Countries

Panama

Outcome results