Ventilator Weaning
Conditions
Keywords
noninvasive mechanical ventilation, ventilator weaning
Brief summary
The investigators use a protocol to wean from noninvasive mechanical ventilation.
Detailed description
Design: Prospective, randomized, controlled trial, with 2 groups: study (protocol weaning group) and control (clinicians' order weaning group). Setting: Respiratory Intensive Care Unit (RICU). Subjects: Patients \>18 yr, noninvasive mechanical ventilation \>24 hours. Interventions and measurements: Study group (weaning as the protocol) and control group (weaning as the clinicians' order); recording of clinical variables at admission and during RICU stay, and end-point variables (noninvasive mechanical ventilation day, RICU and hospital stay, RICU mortality. Expected results: the protocol group's noninvasive mechanical ventilation days is less than clinicians' order group.
Interventions
DEVICEprotocol
In this group, the patients were weaned as the protocol.
OTHERphysician's orders
In this group, the patients were weaned as the clinicians' order.
Sponsors
Duan jun
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SCREENING
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
1. noninvasive mechanical ventilation \> 24 hours. 2. age \>18 years
Exclusion criteria
1. severe cerebraI，heart，hepatic and renal faiIure. 2. facial or cranial trauma or surgery. 3. facial abnormalities. 4. recent gastric or esophageal surgery. 5. active upper gastrointestinal bleeding. 6. large amount of sputum with weak cough ability 7. lack of co-operation.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The duration of noninvasive mechanical ventilation | from admission to ICU to discharge from it (average of 4 weeks) | The duration of noninvasive mechanical ventilation was measured from the patients admitted to ICU to discharged from it,an expected average of 4 weeks. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| The successful weaning rate | from admission to ICU to discharge from it (average of 4 weeks) | The successful weaning rate was measured from the patients admitted to ICU to discharged from it, an expected average of 4 weeks. |
| The length of ICU days | from admission to ICU to discharge from it (average of 4 weeks) | The length of ICU days was measured from the patients admitted to ICU to discharged from it, an expected average of 4 weeks. |
| The intubation rate during the study | from admission to ICU to discharge from it (average of 4 weeks) | The intubation rate during the study was measured from the patients admitted to ICU to discharged from it, an expected average of 4 weeks. |
| The mortality during the study | from admission to ICU to discharge from it (average of 4 weeks) | The mortality during the study was measured from the patients admitted to ICU to discharged from it, an expected average of 4 weeks. |
Countries
China
Outcome results
None listed