Mediators of Inflammation, Prognostic Markers and Genetic Polymorphisms in Patients With Sepsis

Evaluation of Mediators of Inflammation, Prognostic Markers and Genetic Polymorphisms in Patients With Sepsis

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01535534

Acronym

MaSep

Enrollment

250

Registered

2012-02-17

Start date

2012-01-31

Completion date

2021-12-31

Last updated

2020-08-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sepsis

Keywords

sepsis, inflammation, diagnosis, prognosis, survival, mortality

Brief summary

During the past years many investigators have focused on the immunological changes in sepsis disease, and great attention has been paid to the development of practicable means of immunomonitoring. Little is known about diagnostic and prognostic vascular biomarkers during the time course of patients with sepsis.

Detailed description

Primary Outcome Measures: New diagnostic and prognostic markers for septic patients Estimated Enrollment: 300 patients Study Start Date: January 2012 Estimated Study Completion Date: open Estimated Primary Completion Date: open Intervention Details: Procedure: vein puncture comparison of different inflammatory markers in the blood of septic patients

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 90 Years

Healthy volunteers

Yes

Inclusion criteria

* SIRS-Criteria * Proven Infection * One sepsis-induced organ-failure * Adults \< 18 years old

Exclusion criteria

* Anemia * Pregnancy * Blood donor in the last 3 month

Countries

Germany

Outcome results