Fetal Hypoxia
Conditions
Keywords
Hypoxia, Fetal blood sampling, Lactate, pH, base deficit, angiogenic factors, suspected fetal hypoxia
Brief summary
The purpose of this study is to compare lactate and total acid-base status in fetal scalp blood with lactate and total acid-base status in maternal blood and amniotic fluids to provide information on how lactate and base deficit correlates with scalp samples. Furthermore, the investigators want to study whether angiogenic factors in fluids above may be a possible marker of asphyxia during labor.
Interventions
OTHERFetal scalp blood scalp, amniotic fluid, maternal blood and umbilical cord sampling
Fetal blood sampling is conducted when a non reassuring cardiotocographic pattern occurs to detect fetal hypoxia during labor. Amniotic fluid, maternal blood is sampled in cases of fetal blood sampling. Umbilical cord blood sampling is conducted at delivery.
Sponsors
Uppsala County Council, Sweden
Uppsala University Hospital
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 50 Years
Healthy volunteers
Yes
Inclusion criteria
* All deliveries eligible for fetal blood sampling
Exclusion criteria
* Non Swedish speaking * Those who decline to participate in the study
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Hypoxia | 120 seconds | Fetal blood sampling is conducted when a non reassurring cardiotocographic pattern occurs to detect fetal hypoxia during labor |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Subacute hypoxia | 120 seconds | Fetal blood sampling is conducted when a non reasurring cardiotocographic pattern occurs to detect fetal hypoxia during labor |
Countries
Sweden
Contacts
Primary ContactMaria Jonsson, M.D
Backup ContactLena Liljeström, M.D
Outcome results
None listed