Sutured Wounds
Conditions
Keywords
suture, tensile strength, wound care, saline, hydrogen peroxide, skin closure, wounds, wound healing, wound cleansing, antiseptics
Brief summary
Sutures are an integral part of surgery and available materials are diverse, as are the options for post-procedure care. Both saline and hydrogen peroxide are commonly used cleansing agents. This study aims to compare the effect of saline and hydrogen peroxide on the tensile strength of 4-0 nylon sutures following removal from a cutaneous surgical wound.
Interventions
OTHERHydrogen peroxide
Once daily topical application of 3% hydrogen peroxide using a cotton-tipped applicator
OTHERSaline
Once daily topical application of normal saline, using a cotton-tipped applicator
Sponsors
University of Miami
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Caregiver)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Subject is willing to comply with the informed consent procedures * Subject's wound is on the body or scalp * Subject will be able to come to the clinic for suture removal on day 14
Exclusion criteria
* Subject is less than 18 years of age * Subject's wound was not closed with 4-0 nylon sutures * Subject's wound is on the face * Subject plans to apply other topicals to the area under study * Subject's suture is removed before or after day 14
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Tensile strength of 4-0 nylon sutures | 14 days | The tensile strength was defined as the force required to break the suture, with breaking strength as the maximum strength that a material can withstand when subjected to an applied load, without taking into consideration the cross sectional area. The strength of the sutures was measured using a tensometer. |
Countries
United States
Outcome results
None listed