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Making Memory Better for Seniors With Mild Cognitive Impairment

Neuropsychological Intervention for a Seniors Mental Health Population With Mild Cognitive Impairment

Status
Active, not recruiting
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT01532739
Enrollment
40
Registered
2012-02-14
Start date
2011-12-05
Completion date
2025-12-05
Last updated
2024-08-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mild Cognitive Impairment

Keywords

Mild Cognitive Impairment, Aging, Memory, Executive Function, Cognitive Intervention, Memory Training, Mental Health

Brief summary

The purpose of this study is to investigate the feasibility and effectiveness of a cognitive training group in individuals with Mild Cognitive Impairment, using a new paradigm that will optimize ecological validity by (1) focusing on everyday memory problems, (2) supplementing traditional memory training with the teaching of an empirically-supported problem-solving approach, and (3) employing a clinically representative sample of individuals with MCI (e.g., not excluding those with mild affective symptoms).

Interventions

BEHAVIORALCognitive training

The cognitive training consists of 10 weekly 2-hour sessions. It is run with groups of MCI participants and their study partners (who help with reinforcing the strategies in everyday activities). The program provides information about memory and lifestyle factors in the first two weeks, followed by training and practice over the next eight weeks on empirically-supported cognitive strategies known to be effective at supporting day-to-day remembering in MCI. Participants learn to apply a core set of strategies (spaced retrieval, memory book logging) across a variety of common memory problems (e.g., remembering names, appointments, etc). To enhance the likelihood that these strategies will transfer to other settings beyond training, participants are also taught a memory problem solving approach that will cue them to recognize situations in which they need to: (1) stop and remember something, (2) select and apply an appropriate memory strategy, and (3) monitor that it is working.

Sponsors

Nova Scotia Health Research Foundation
CollaboratorOTHER_GOV
Nova Scotia Health Authority
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Healthy volunteers
No

Inclusion criteria

* Clinical diagnosis of Mild Cognitive Impairment

Exclusion criteria

* Clinical diagnosis of dementia * History of neurological conditions known to impair cognition * History of alcohol or drug abuse * History of chronic psychiatric illness * Current symptoms of moderate to severe depression (Geriatric Depression Scale \>19) or anxiety (Beck Anxiety Inventory \>15)

Design outcomes

Primary

MeasureTime frameDescription
Change in everyday memory functioningMeasured at baseline and months 3, 5, 8Rivermead Behavioural Memory Test (3rd Edition)

Secondary

MeasureTime frameDescription
Change in caregiver burdenMeasured at baseline and months 3, 5, 8Zarit Burden Interview
FeasibilityMeasured at end of studyRecruitment, retention, and compliance rates
Change on traditional memory testingMeasured at baseline and months 3, 5, 8California Verbal Learning Test (2nd Edition)
Change in quality of lifeMeasured at baseline and months 3, 5, 8Zarit Burden Interview
Change in mood (i.e., self-report symptoms of depression)Measured at baseline and months 3, 5, 8Geriatric Depression Scale
Change in mood (i.e., self-report symptoms of anxiety)Measured at baseline and months 3, 5, 8Beck Anxiety Inventory
Change in other psychiatric symptoms (informant-report)Measured at baseline and months 3, 5, 8Neuropsychiatric Inventory
Change in memory perceptionMeasured at baseline and months 3, 5, 8Multifactorial Metamemory Questionnaire

Countries

Canada

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026