Oral Sodium Blood Pressure in Normal Weight, Overweight and Obese Volunteers

Simplification of the Test of Sensibility in the Salt: Preliminary Study at the Child and the Adult

Status

Completed

Phases

Phase 2

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01532401

Acronym

PLADSEL

Enrollment

Registered

2012-02-14

Start date

2011-03-31

Completion date

Unknown

Last updated

2016-10-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obesity

Keywords

Blood pressure

Brief summary

The primary objective of this study is to analyze the sensitivity of blood pressure to oral salt intake. Matched male and female participants will be selected as normal weight, overweight, and obese. Participating subjects will have a first visit with blood pressure measurement and a blood sample. In two consecutive phases of one week, subjects will receive 12 pills of sodium (6 grams) or corresponding placebo. Blood pressure will be measured at the end of each phase.

Interventions

OTHERsodium chloride

sodium chloride 500mg

OTHERMethylcellulose crystalline

Methylcellulose 37 ml

Eligibility

Sex/Gender

ALL

Age

6 Years to 45 Years

Healthy volunteers

Inclusion criteria

* Informed consent * Age 18-45 for adults and 6-8 for children

Exclusion criteria

* African ethnicity (known to affect blood pressure sensitivity to salt) * Chronic condition affecting blood pressure * Diabetes (known to affect blood pressure sensitivity to salt) * Hypertension

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026