IL-10 Levels and Remote Ischemic Preconditioning in Acute Myocardial Infarction

Interleukin-10 Levels and Remote Ischemic Preconditioning in Acute Myocardial Infarction.

Status

Terminated

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01532206

Enrollment

Registered

2012-02-14

Start date

2013-03-31

Completion date

2014-05-31

Last updated

2016-03-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Myocardial Infarction

Keywords

Remote ischemic preconditioning, inflammation

Brief summary

Remote ischemic preconditioning has proven beneficial in patients undergoing percutaneous coronary intervention and coronary artery bypass surgery. Animal studies suggest remote ischemic preconditioning increases levels of interleukin 10. The investigators aim to determine whether remote ischemic preconditioning results in an increase in IL-10 levels in patients following acute myocardial infarction.

Interventions

OTHERBlood pressure cuff insufflation

Blood pressure cuff will be inflated to a pressure of 200mmHg for 5 minutes. This will be repeated x 3, separated by 5 minutes.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

\- Acute myocardial infarction

Exclusion criteria

\- Cardiogenic shock Active ischemia

Design outcomes

Primary

Measure	Time frame
Interleukin 10 levels	24 hours following RIPC

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026