Difficult Intubation
Conditions
Keywords
Difficult intubation, Intensive care units, Risk factors, Incidence, Complications, Intubation in Intensive Care Unit, More than 2 attempts of intubation, Intubation attempts lasting more than 10 minutes
Brief summary
Difficult intubation is challenging in intensive care units. There are limited data regarding risk factors of difficult intubation in ICU. The primary purpose of the investigators study is to assess the risk factors of difficult airway in adults in ICU.
Detailed description
PURPOSE: Intubation in ICU strongly differs from intubation in operative rooms. The results of studies about risk factors of difficult intubation performed in operative rooms cannot therefore be extrapolated directly to ICU. The primary purpose of this trial (cf Part Design of this registration) is other and more particularly Prognosis because it is is an assessment of risk factors of difficult airway in intensive care units. DESIGN AND METHODOLOGY: This is an open prospective multicentric study of intubation in ICU in more than 50 centres. Consecutive intubations will be included in each centre, in order to reach the sample size required (at least 1000 procedures intubations). The usual risk factors of difficult intubation in operative rooms, the demographic parameters and the complications of intubation will be assessed, as well as survival status at 28 days.
Interventions
PROCEDUREINTUBATION IN INTENSIVE CARE UNIT
Standard intubation procedure used in Intensive Care Unit
Sponsors
University Hospital, Montpellier
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
OTHER
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* More or equal to 18 years old * Men and women * Informed patient * Affiliated or benefit from an disease insurance * Available for a 28 days follow-up * Intubated patients in Intensive Care Unit
Exclusion criteria
* Law protected patients * Opposed to participate to study
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Difficult intubation | until to 10 minutes | According to ASA criteria, difficult intubation is measured by attempts lasting more than 10 min or more than two attempts |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Complications of intubation in ICU | up to one hour after intubation | * Respiratory (inhalation, oesophageal intubation, SpO2\<80%) * Hemodynamic(SAP\<65 mm Hg, elevated or low cardiac frequency,rythm troubles, heart attack), * Neurologic (agitation), * Local (dental trauma, laryngal trauma), * Death * Complications occuring during one hour after intubation: respiratory (major desaturation: SpO2\<80%, pneumothorax, persistent hypoxia with SpO2\<80%), hemodynamic (persistent hypotension: SAP\<90 mm Hg despite of vascular filling, rythm troubles, heart attack, introduction or majoration of amines posology), neurologic(agitation), death |
| Mortality at 28 days after difficult intubation | up to 28 days after difficult intubation | Survival status at Day 28 or date of death if patient dead before. |
| Incidence of difficult intubation in ICU | up to day 28 | — |
Countries
France
Outcome results
None listed