Mapping Multidimensional Illness Trajectories of Patients With End-stage Kidney Disease

Mapping Multidimensional Illness Trajectories of Patients With ESKD

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01530945

Enrollment

227

Registered

2012-02-10

Start date

2012-03-31

Completion date

2015-07-31

Last updated

2015-09-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

End Stage Kidney Disease

Brief summary

Patients with end-stage kidney disease (ESKD) must manage not only the demands of dialysis and comorbid conditions but also associated symptoms and acute life-threatening events that contribute to functional limitations and increased risk of mortality. Yet little is known about the trajectories of quality of life dimensions in patients with ESKD when they experience acute life-threatening episodes, to guide palliative care for this population. In this prospective, descriptive study, we will identify trajectories of symptoms, physical functioning, psychosocial needs, and emotional and spiritual well-being in 200 patients with ESKD who are at a high risk of experiencing acute life-threatening events and mortality within 12 months.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* aged 18 years or older; * receiving either Hemodialysis or Peritoneal dialysis * on dialysis either \< 3 months or ≥ 6 months with a Charlson Comorbidity Index (CCI) score ≥ 5

Exclusion criteria

* Patients who are enrolled in hospice or too sick to participate in questionnaire completion will not be eligible. * Kidney transplant candidates will be excluded because their illness trajectories after transplant are likely to differ.

Design outcomes

Primary

Measure	Time frame
Symptoms, physical functioning, psychosocial needs, spiritual well-being, cognitive functioning	12 months

Countries

United States

Outcome results