Respiratory Insufficiency
Conditions
Keywords
Respiratory Insufficiency [C08.618.846]
Brief summary
The study aims to assess the agreement between respiratory mechanics parameters measured noninvasively by means of brief airways occlusions at the beginning of inspiration and the reference parameters obtained with standard techniques of esophageal and gastric pressure under static and dynamic conditions in a mixed population of ICU patients mechanically ventilated in pressure support ventilation mode.
Interventions
OTHERInvasive method
Esophageal and gastric catheters to measure respiratory mechanics (static and dynamic)
OTHERNon invasive method
Non\_invasive method: airway pressure measured during a 150-200 ms at the beginning of inspiration
Sponsors
University of Turin, Italy
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* intact respiratory drive; * PaO2/FiO2 ratio \> 150 with a positive end-expiratory pressure (PEEP) ≤ 8 cmH2O; * pH between 7.35 and 7.45; * patient alert, conscious, and cooperative with a Glasgow Coma Scale ≥ 10.
Exclusion criteria
* infection, sepsis or septic shock; (with fever no) * hemodynamic instability; * respiratory centres depression; * esophageal deformity, or gastric/esophageal illnesses; * previous recent gastric/esophageal surgery.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Non-invasive respiratory mechanics measurement | 2 hours | use of 150-200 ms airway occlusions at the beginning of inspiration to measure non-invasive respiratory mechanics |
Contacts
Primary ContactVito Marco VM Ranieri, MD
Backup ContactGabriela G Ferreyra, MSC
Outcome results
None listed