Comparison of Bowel Cleansing Methods for Colonoscopy in Hospitalized Patients

Efficacy of Bisacodyl Given as Part of a Polyethylene Glycol-based Bowel Preparation Prior to Colonoscopy in Hospitalized Patients

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01528098

Acronym

PEG

Enrollment

600

Registered

2012-02-07

Start date

2012-03-31

Completion date

2012-10-31

Last updated

2012-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intestine; Complaints

Keywords

polyethylene glycol, bisacodyl

Brief summary

The purpose of this study is to compare two regimens of polyethylene glycol(PEG) plus bisacodyl versus PEG alone for bowel preparation in hospitalized patients.

Detailed description

Inadequate bowel preparation may lead to a longer colonoscopy, and to an inability to identify lesions. PEG can provide a rapid orthograde peroral approach to colonic lavage without producing significant fluid or electrolyte changes. Thus PEG is now commonly used for bowel preparation. However, large amounts and unsatisfactory taste of PEG solution are generally poorly tolerated, especially in hospitalized patients who had comorbidity and restricted ambulation. Recently, a new PEG-based bowel cleansing agents became available. It combines PEG with a high dose of ascorbic acid or bisacodyl. Although many studies reported the efficacy of these combined solution for colonoscopy, but efficacy in hospitalized patients was under-recognized.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

20 Years to 80 Years

Healthy volunteers

Yes

Inclusion criteria

* Hospitalized patients for colonoscopy

Exclusion criteria

* age under 20 years or over 80 years * major psychiatric illness * known allergy to PEG * serious condition- severe cardiac, renal, or metabolic diseases * partial colon resection * current acute exacerbation of chronic inflammatory bowel disease * functional constipation defined by Rome III diagnostic criteria

Design outcomes

Primary

Measure	Time frame	Description
The efficacy of bowel preparation	one day (after colonoscopy)	Ottawa scale

Secondary

Measure	Time frame	Description
Patient's compliance and acceptability	one day (after injestion of preparation solution)	acceptability, Visual Analogue Scale
Patient's compliance and acceptability (2)	one day (after injestion of preparation solution)	stress for ingestion, Stress 0(not) - 4(severe)
Patient's compliance and acceptability (3)	one day (after colonoscopy)	willingness for re-evaluation, 0(very willing) - 4(some)

Contacts

Primary ContactDong Il Park, professor

diksmc.park@samsung.com82-2-2001-2059

Outcome results