Heparin Solution and INTEM/HEPTEM Analysis

Influence by Heparinized Flush Solution of the Radial Artery Catheter: INTEM and HEPTEM Analysis.

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01522846

Enrollment

Registered

2012-02-01

Start date

2012-01-31

Completion date

2013-01-31

Last updated

2013-08-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Brain Tumor, Cerebral Artery Anuerysm, Spinal Stenosis

Brief summary

Heparinized solution has been used for maintenance of arterial catheter during perioperative period. Although the infused dose of heparin is very low, the investigators examine whether the heparin effect is remained or not in blood using rotational thromboelastometry (ROTEM) analysis.

Interventions

DRUGHeparin

Heparinized flush solution contained heparin concentration of 2 unit/ml and continuous flow of the flush solution was 5 ml/h at 300 mmHg.

Study design

Observational model

CASE_ONLY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

20 Years to No maximum

Healthy volunteers

Inclusion criteria

* Patients requiring continuous invasive arterial pressure monitoring during operation for anesthetic management.

Exclusion criteria

* heparin hypersensitivity * hematologic disease * anticoagulant medication

Design outcomes

Primary

Measure	Time frame	Description
INTEM test	at 30 min before operation and 30 min after operation	INTEM is not an abbriviation. INTEM is one of the ROTEM test and it is an coagulation test name (such as prothrombin time test) using patient's whole blood. We put the blood sample of patinet into the machine, so the result comes out automatically. It will be checked twice at pre- and postopertive 30 minute and it'll be analyzed and compared.
HEPTEM test	at 30 min before operation and 30 min after operation	HEPTEM is not an abbriviation. HEPTEM is one of the ROTEM test and it is an coagulation test name (such as prothrombin time test) using patient's whole blood. We put the blood sample of patinet into the machine, so the result comes out automatically. It will be checked twice at pre- and postopertive 30 minute and it'll be analyzed and compared.

Secondary

Measure	Time frame
Total infused units of heparin	periond from starting operation to finishing operation (espected average of 5 hours).

Countries

South Korea

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026