Advanced Characterization of Autosomal Dominant Optic Atrophy

Cross Sectional Study of Autosomal Dominant Opticus Atrophy

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01522638

Enrollment

Registered

2012-01-31

Start date

2011-12-31

Completion date

2015-06-30

Last updated

2012-01-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Optic Atrophy, Autosomal Dominant

Brief summary

The purpose of this study is to determine the anatomy of the retina and the optic nerve in patients with autosomal dominant optic atrophy (ADOA). Based on these findings the aim of the study is to determine why patients with the same type of genetic material, i.e. the same mutation, have such large variations of symptoms, spanning from unaffected subjects to blindness. The project requires examination of both healthy and affected family members.

Interventions

None listed

Study design

Observational model

FAMILY_BASED

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Age

8 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* Subjects diagnosed with autosomal dominant optic atrophy

Exclusion criteria

* Age below 8 years old

Design outcomes

Primary

Measure	Time frame
visual acuity	1 day
vessel caliber	1 day
OCT	1 day
Microperimetry	1 day
Lifestyle questionnaire	1 day
General checkup	1 day

Countries

Denmark

Outcome results