THRA_hematologic Variables

Relations Between Hematologic Variables and Postoperative Bleeding in Total Hip Replacement Arthroplasty

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01521858

Enrollment

Registered

2012-01-31

Start date

2012-01-31

Completion date

2013-02-28

Last updated

2013-08-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Avascular Necrosis of Hip

Brief summary

Total hip replacement arthroplasty is a surgery having intra- and postoperative substantial blood loss. The investigators will investigate the relationship between the various hematologic variables and postoperative bleeding volume.

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

20 Years to 80 Years

Healthy volunteers

Inclusion criteria

* avascular necrosis of hip * total hip replacement arthroplasty

Exclusion criteria

* revision operation * hematologic disease * anticoagulant medication * preoperative hemoglobin \< 10 g/dl * preoperative transfusion of red blood cells

Design outcomes

Primary

Measure	Time frame
Rotational thromboelastometry	preoperative 1 day and postoperative 1 day
prothrombin time_international normalized ratio	preoperative 1 day and postoperative 1 day
activated partial prothrombin time	preoperative 1 day and postoperative 1 day
fibrinogen concentration	preoperative 1 day and postoperative 1 day
postoperative bleeding volume	at first postoperative day
Hemoglobin	preoperative 1 day and postoperative 1 day
hematocrit	preoperative 1 day and postoperative 1 day
platelet	preoperative 1 day and postoperative 1 day

Secondary

Measure	Time frame	Description
intraoperative urine output	Period from starting to finishing the operation (During operaiton, an expected average of 3 hours)	—
transfusion units	Period from starting to finishing the operation (During operaiton, an expected average of 3 hours) and postoperative first day	Red blood cell
volume of infused fluid during operation	Period from starting to finishing the operation (During operaiton, an expected average of 3 hours)	Infused total crystalloid and colloid volume during the operation will be recorded.

Countries

South Korea

Outcome results