Natural History of Carotid Atherosclerosis

A Prospective Natural History Study of Carotid Atherosclerosis

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01521351

Enrollment

700

Registered

2012-01-30

Start date

2012-01-31

Completion date

2020-12-31

Last updated

2019-09-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Angina Pectoris, Carotid Artery Disease, Myocardial Infarction, Stroke

Keywords

microwave radiometry, cardiovascular events, carotid artery disease, stroke, myocardial infarction

Brief summary

A prospective study of 700 patients with coronary artery disease will undergo non invasive evaluation of their carotid arteries by ultrasound and microwave radiometry. The patients will be followed up for 3 years and their outcome regarding the cardiovascular events (death, cardiac events, cerebrovascular events) will be recorded

Detailed description

Carotid artery Thermal heterogeneity recorded by MR will be corelated to cardiovascular events (death, cardiac events, cerebrovascular events) as well as to all demographic (age, sex, hypertension, dyslipidemia, smoking status, etc) factors

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

30 Years to 80 Years

Healthy volunteers

Inclusion criteria

* Consecutive patients with coronary artery disease admitted in our hospital

Exclusion criteria

* Patients with history of previous cerebrovascular event, * History of vasculitis, intermittent inflammatory, infectious, or neoplastic conditions likely to be associated with an acute-phase response.

Design outcomes

Primary

Measure	Time frame	Description
To detect if carotid ultrasound and carotid microwave radiometry measurements can predict the incidence of cerebrovascular and cardiovascular events in patients with coronary artery disease	3 years	Microwave radiometry is a non invasive and safe technique that measures temperature of the internal tissues by detecting the normal radiation of the tissues in microwave frequencies. The primary outcome of the study is to see if the temperatures measured in the carotid arteries of patients with coronary artery disease can predict their outcome regarding cerebrovascular and cardiovascular events

Secondary

Measure	Time frame
Relation of other demographic factors with carotid ultrasound and microwave radiometry measurements and outcome	3 years

Countries

Greece

Contacts

Primary ContactKonstantinos Toutouzas

ktoutouz@gmail.com

Backup ContactAndreas Synetos

synetos@yahoo.com

Outcome results