Comparison of Diagnostic Accuracy for Predicting Histology of Colorectal Lesions

Comparison of Diagnostic Accuracy for Predicting Histology of Colorectal Lesions Using Magnifying Colonoscopy With Narrow Band Imaging, Indigo Carmine, and Acetic Acid Staining

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01521091

Enrollment

565

Registered

2012-01-30

Start date

2009-01-31

Completion date

2010-12-31

Last updated

2025-10-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal Neoplasms

Keywords

narrow band imaging（NBI）, indigo carmine, acetic acid, colorectal lesions, predicting histology

Brief summary

Chromoendoscopy (indigo carmine or acetic acid) and Narrow Band Imaging (NBI) could make accurate evaluation in predicting of invasive depth of colorectal neoplasia. NBI could be the first choice.

Detailed description

To compare the diagnostic accuracy of chromoendoscopy indigo carmine or acetic acid and NBI for differentiating neoplastic from non-neoplastic colorectal lesions, differentiating adenomas from carcinomas, and differentiating early carcinomas from invasive ones. Included colorectal lesions consecutively distribute in a 1:1 ratio to 2 groups.

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 90 Years

Healthy volunteers

Inclusion criteria

* Consecutive patients with more than one lesion ≧ 6mm .

Exclusion criteria

* Patients with chronic inflammatory bowel disease, advanced cancer, insufficient bowel preparation, familial adenomatous polyposis (FAP) * Lesions ≦ 5mm and submucosal tumor (SMT).

Countries

China

Outcome results