Oligospermia
Conditions
Brief summary
The vitamin,minerals and amino acid supplementation for 3 months will improve the semen parameters,fertilization rate and embryo quality in subfertile men undergoing IVF treatment
Detailed description
With the supplement intake containing amino acids, vitamins and minerals designed to improve sperm parameters, the couples undergoing IVF treatment will benefit as the change and improvement of sperm parameters will increase the fertilization rate and improve the embryo quality thus allowing shorter time for pregnancy achievement and less frustration with long duration of treatments
Interventions
DIETARY_SUPPLEMENTVitamale
men will receive the vitamale dietary supplement compared to a sham pill
Sponsors
Hillel Yaffe Medical Center
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Masking
TRIPLE (Subject, Caregiver, Investigator)
Eligibility
Sex/Gender
MALE
Age
20 Years to 50 Years
Healthy volunteers
Yes
Inclusion criteria
* healthy male age 20-50 * at least one IVF cycle without pregnancy * sperm parameters: * Oligospermia 5-20\*106 * Teratospermia 6-14% normal forms * Asthenospermia \<30% motility
Exclusion criteria
* female factor infertility * age \> 50 or under 20 * testicular problem on physical examination * history of malignancy and /or chemotherapy * usage of antiandrogen/testosterone * history of drug abuse/alcohol * a known endocrinological problem * current STD or genitourinary infection * Retrograde Ejaculation * Y chromosome microdeletion * Karyotype abnormalities
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Sperm parameters | 3 months of treatment | Men suffering from a male factor problem and after one failed IVF treatment will be given the supplement for 3 months after which the sperm parametrs will be evaluated and compared to pre-supplement data and later the embryo quality and fertilization rate will reviewed analyzed and compared |
Countries
Israel
Outcome results
None listed