Anxiety and Depression in Patients Hospitalizes for an Acute Exacerbation of COPD

A Prospective Randomized Trial to Asses the Efficacy of an Early Psychiatric Counseling Compared to Usual Care in a Cohort of Patients Hospitalized for an Acute Exacerbation of COPD in Prevention of Re-exacerbation

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01520376

Acronym

ADPHA-EPOC

Enrollment

169

Registered

2012-01-27

Start date

2011-10-31

Completion date

2014-04-30

Last updated

2018-07-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anxiety, Chronic Obstructive Pulmonary Disease, Depression

Brief summary

This study will try to elucidate wheter the impact of a psychiatric intervention in patients hospitalized because an acute exacerbation of COPD and anxiety/depression and reconsulting at 1 and 6 month after discharge.

Interventions

BEHAVIORALCounselling

Visit by a psychiatrist at day-30 and day-180 after discarge

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

SUPPORTIVE_CARE

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

ALL

Age

40 Years to 90 Years

Healthy volunteers

Inclusion criteria

* Men and women of any ethnic group * Above 40 years old * Diagnose with Chronic Obstructive Pulmonary disease (COPD) according to the ATS/ERS guidelines * Acute exacerbation of COPD according to the following criteria: a) Cyanosis b) Obnubilations or mental confusion d) Respiratory Rate above 25 per minute e) Failure of ambulatory treatment f) Co-morbidities that worsens respiratory condition g) Dyspnea

Exclusion criteria

* Less than 6 months expectancy of life * Needing of mechanical ventilation * Severe cardiovascular disease * Pregnancy * Previous diagnosis of depression/anxiety

Design outcomes

Primary

Measure	Time frame	Description
Efficacy of the intervention	6 months	Counselling vs. usual care on re-hospitalizations

Secondary

Measure	Time frame	Description
Impact of diagnosis	6 months	Anxiety/depression diagnosis on number of exacerbations at 1 and 6 months, comparing patients with screening on HADS test \> 12

Countries

Spain

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026