Vitamin D Deficiency
Conditions
Keywords
Vitamin D, Cholecalciferol, Supplementation, Dietary Supplements, Dietary Fats, 25-hydroxyvitamin D
Brief summary
The purpose of this study is to evaluate the absorption of dietary supplement of vitamin D3 (cholecalciferol), through the variation of 25 (OH) D levels, as the fat content of the meal associated with the administration of the supplement.
Interventions
DIETARY_SUPPLEMENTVitamin D3
Supplement of vitamin D3
DIETARY_SUPPLEMENTPlacebo
Placebo
Sponsors
Hospital de Clinicas de Porto Alegre
Conselho Nacional de Desenvolvimento Científico e Tecnológico
Federal University of Rio Grande do Sul
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
ALL
Age
18 Years to 40 Years
Healthy volunteers
Yes
Inclusion criteria
Residents of the hospital clinics of Porto Alegre
Exclusion criteria
* Don't drink milk * Obesity * Malnutrition * Liver disease * Kidney disease or diabetes * Use of dietary supplements containing calcium and vitamin D * Medications * Anticonvulsants * Barbiturates, or steroids. * Having performed a journey the last four months to locations near the Earth's equatorial plane, due to sun exposure that may have occurred during this period, or vacations planned during the study period.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change from baseline in serum 25(OH)D at 14 day after intervention | Change from baseline in serum 25(OH)D at 14 days | 25(OH)D response to supplemental vitamin D3 |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change from baseline in Parathyroid hormone at 14 days after intervention | Change from baseline in Parathyroid hormone at 14 days | Parathyroid hormone response to supplemental vitamin D3 |
Outcome results
None listed