Ankylosing Spondylitis, Osteoarthritis, Rheumatoid Arthritis
Conditions
Keywords
Osteoarthritis, Rheumatoid Arthritis, Ankylosing Spondylitis
Brief summary
The primary objective of this cross-sectional observational real life study is to investigate the patient reported adherence to PPI, when prescribed as prevention of NSAID associated GI Ulcers to patients prescribed a NSAID. Patients included have Osteoarthritis, Rheumatoid Arthritis or Ankylosing Spondylitis. Adherence will be assessed by patient questionnaires.
Detailed description
Cross-sectional, observational Real Life study on NSAIDs treated patients with Osteoarthritis, Rheumatoid Arthritis and Ankylosing Spondylitis: Assessment of patient adherence to PPI treatment
Interventions
None listed
Sponsors
AstraZeneca
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Confirmed diagnosis (documented in the medical record) of OA, RA or AS * Prescription of oral NSAID treatment for OA, RA or AS, where low dose is not sufficient * Prescription of PPI for prevention of NSAID associated GI ulcers, with instruction to take PPI same day as when taking NSAID.
Exclusion criteria
* Participating in any clinical trial involving PPI or NSAID * Patients prescribed PPI as acute treatment of GI events or symptoms within 8 weeks * Inability to complete PROs
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Patient reported adherence to PPI treatment on actual days of NSAID treatment. | 7 days |
Secondary
| Measure | Time frame |
|---|---|
| Proportion of patients with reported adherence ≤ 80%. | 7 days |
| Patient adherence to prescribed ASA treatment. | 7 days |
Countries
Sweden
Outcome results
None listed