Gastroparesis
Conditions
Keywords
gastroparesis, gastric emptying, antro-duodenal manometry
Brief summary
Impaired gastric emptying may cause dyspeptic symptoms including nausea, vomiting and even nutritionnal impairment. Delay in gastric emptying may result from antro-pyloro-duodenal motility impairement.
Detailed description
The aim of this study is therefore to measure antro-pyloro-duodenal motor activity in patients with idiopathic gastroparesis.
Interventions
None listed
Sponsors
University Hospital, Rouen
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
Yes
Inclusion criteria
* Idiopathic gastroparesis or healthy volunteers * Idiopathic gastroparesis must have delayed gastric emptying shown using C13 breath test
Exclusion criteria
* Diabetic or post-surgical gastroparesis * Treatment modifying GI motility (prokinetics, opioids...) * Parkinson or neurologic disease * Evoluting inflammatory process or neoplasia * Treatment modifying coagulation * Patients not affiliated to the French healthcare insurance
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| antro-pyloro-duodenal pressure | 3h | the main outcome is the pressure measured using pressure sensors within the antrum, the pylorus, and the first part of the duodenum. This will be measured during 3h fast. Pressures measured in the antrum, the pylorus, and the duodenum wiil be compared between healthy volunteers and gastroparetic patients |
Countries
France
Outcome results
None listed