LOXL1 Polymorphism in Pseudoexfoliation Syndrome

Evaluation of LOXL1 Polymorphism in Pseudoexfoliation Syndrome in the Korean Population

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01515735

Enrollment

Registered

2012-01-24

Start date

2011-12-31

Completion date

2012-12-31

Last updated

2012-01-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pseudoexfoliation Syndrome

Brief summary

To evaluate the association profiles of the lysyl oxidase-like 1 gene polymorphisms with pseudoexfoliation syndrome in the Korean population, Genotypes of lysyl oxidase-like 1 gene were analyzed by direct sequencing.

Detailed description

To evaluate the association profiles of the lysyl oxidase-like 1 gene polymorphisms with pseudoexfoliation syndrome in the Korean population, peripheral blood sampling will be done from the patients with pseudoexfoliation. And genotypes of the three single nucleotide polymorphisms of lysyl oxidase-like 1 gene , rs1048661, rs3825942, rs2165241 were analyzed by direct sequencing.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

20 Years to 70 Years

Healthy volunteers

Inclusion criteria

* Clinical diagnosis of Pseudoexfoliation

Exclusion criteria

* medical condition that peripheral blood sampling cannot be done

Design outcomes

Primary

Measure	Time frame	Description
Genotypes of the three single nucleotide polymorphisms of LOXL1 (rs1048661, rs3825942, rs2165241)	about 1 year (when all patients were recruited)	Genotypes of the three single nucleotide polymorphisms of LOXL1 were analyzed by direct sequencing, after obtained from the peripheral blood sampling from patients.

Countries

South Korea

Contacts

Primary ContactChangwon Kee, M.D., Ph.D.

ckee@skku.edu82-2-3410-3564

Outcome results