Postoperative Anemia and Functional Outcomes After Fast-track Primary Hip Arthroplasty

Postoperative Anemia and Functional Outcomes After Fast-track Primary Hip Arthroplasty - a Prospective Observational Study

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01514006

Enrollment

125

Registered

2012-01-20

Start date

2012-01-31

Completion date

2013-08-31

Last updated

2015-03-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anemia, Arthroplasty, Hip Replacement

Keywords

Primary hip arthroplasty, postoperative anemia, functional outcomes

Brief summary

The purpose of this study is to evaluate the possible association between postoperative anaemia and functional outcomes the first 2 weeks after primary hip arthroplasty. The investigators hypothesise that patients with a higher degree of postoperative anaemia have impaired postoperative rehabilitation as measured by standardized functional outcome tests.

Detailed description

Postoperative anemia may impair postoperative rehabilitation due to anemia related symptoms such as fatigue or dizziness. Although, the impact of postoperative anemia on postoperative rehabilitation and function has previously been examined the results are conflicting. Patients undergoing fast-track hip arthroplasty (THA) are mobilized early and participate in physiotherapy during the admission but are discharged early (2-3) days postoperative. However, the ability to rehabilitate early after discharge has not been evaluated in relation to postoperative anemia. The purpose of this observational study is to evaluate the possible association between postoperative anaemia and functional outcomes the first 2 weeks after primary hip arthroplasty. The investigators hypothesise that patients with a higher degree of postoperative anaemia have impaired postoperative rehabilitation as measured by standardized functional outcome tests. Hb concentrations and functional outcome measurements will be performed preoperatively, at the day of hospital discharge and during a postoperative visit 12-16 days after surgery.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

65 Years to No maximum

Healthy volunteers

Inclusion criteria

* Patients undergoing primary unilateral THA * Age 65 or older

Exclusion criteria

* Not able to give consent * Not able to walk prior to surgery * Chronic need for RBC transfusion

Design outcomes

Primary

Measure	Time frame	Description
6 Minute walking test (6MWT)	2 weeks after surgery	6MWT is a standardized functional test which determines the walking distance covered during a timed period of 6 minutes.

Secondary

Measure	Time frame	Description
FACT-Anemia Scale	2 weeks after surgery	FACT-Anemia scale is a validated questionare based score addressing anaemia related symptoms.
Timed up and go test (TUG)	2 weeks after surgery	—
At home activity by ActivPal	1 week after surgery	Activity measures using accelerometer based activity monitor

Countries

Denmark

Outcome results