The Effect of Dexmedetomidine on the Emergence Agitation in Nasal Surgery

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01513772

Enrollment

100

Registered

2012-01-20

Start date

2012-02-29

Completion date

2012-08-31

Last updated

2012-08-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Airway Extubation

Brief summary

The investigators examined the effect of dexmedetomidine on the emergence agitation and postoperative quality of recovery in nasal surgery

Detailed description

Emergence agitation during the immediate postanesthetic period is common. It may lead to serious consequences for the patient, such as injury, increased pain, hemorrhage, self-extubation, and removal of catheters. Emergence agitation is common in ENT surgery. The aim of this study is to evaluate the effect of dexmedetomidine on the emergence agitation and postoperative quality of recovery in adult patients undergoing nasal surgery.

Interventions

DRUGDexmedetomidine

Dexmedetomidine(4㎍/mL) : 0.4㎍/kg/hr infusion until extubation

DRUGNormal saline 0.9%

Normal saline(guess as 4㎍/mL) : 0.4㎍/kg/hr infusion until extubation

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

TRIPLE (Subject, Caregiver, Investigator)

Eligibility

Sex/Gender

ALL

Age

20 Years to 59 Years

Healthy volunteers

Inclusion criteria

* age ≥ 20, * ASA class I and II, * nasal surgery

Exclusion criteria

* bradycardia (\< 45 bpm), * heart block, * liver failure, * renal failure, * uncontrolled hypertension, * body mass index ≥ 30 kg/m2

Design outcomes

Primary

Measure	Time frame
Emergence agitation	20min

Secondary

Measure	Time frame
Postoperative quality of recovery	1 day

Countries

South Korea

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026