Cycled Light and Crying of Preterm Infants

Cycled Light Exposure Reduces Fussing and Crying in Very Preterm Infants

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01513226

Enrollment

Registered

2012-01-20

Start date

2006-06-30

Completion date

2008-09-30

Last updated

2012-01-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Crying, Sleep

Keywords

cycled light, dim light, circadian rhythm, actigraphy, sleep, premature infant

Brief summary

This study shows that cycled light during neonatal care reduces infant's fussing and crying behavior at 5 and 11 weeks corrected age and improves growth during neonatal care.

Interventions

OTHERCycled light

lights on at daytime, lights off at nighttime

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

SUPPORTIVE_CARE

Masking

NONE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* very preterm infants (≤ 32 0/7 weeks gestational age, GA)

Exclusion criteria

* major cerebral injuries such as intraventricular haemorrhage grade III (according to Papile 16) or periventricular leukomalacia or venous infarction (according to Govaert and de Vries 17) diagnosed by cranial ultrasound * retinopathy of prematurity grade III and IV * congenital malformations * small for gestational age (birth weight \< 3rd percentile) * prenatal infections * intrauterine drug exposure

Design outcomes

Primary

Measure	Time frame	Description
mean duration and change over time for total duration per 24 hours for crying variables	5 and 11 weeks corrected age	mean duration per 24 hours for following variables: content, fussing, crying, unsoothable crying change over time, measured at 5 and 11 weeks corrected age measured by diary

Secondary

Measure	Time frame	Description
mean sleep duration per 24 hours and change over time	5,11 and 25 weeks corrected age	mean sleep duration per 24 hours measured by sleep diary measured at 5, 11 and 25 weeks corrected age, for adressing change over time
mean weight gain per day	during hospital stay	mean weight gaing per day during hospital stay.
mean activity count per 24 hours and change over time	5, 11, and 25 weeks corrected age	mean activity count per 24 hours measured by actigraph recordings measured at three time points, 5, 11 and 25 weeks corrected age to adress change over time

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 19, 2026