Correlation of PaCO2 to the Inspired and Expired Oxygen Gradient

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01513213

Acronym

O2 Fraction

Enrollment

Registered

2012-01-20

Start date

2011-10-31

Completion date

2016-12-31

Last updated

2017-01-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Neurosurgery

Keywords

Arterial cannulation, Blood gas, Carbon dioxide, Arterial blood, Oxygen, Oxygen fractions

Brief summary

The purpose of this study is to evaluate whether a correlation exists between the partial pressure of carbon dioxide existing within arterial blood and the gradient between inhaled and exhaled fractions of oxygen.

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Age

18 Years to 65 Years

Healthy volunteers

Inclusion criteria

* Age 18 to 65. * Scheduled for surgical procedure that will last at least 2 hours. * Arterial cannulation is planned because of either the complexity of the surgery or patient comorbidity. * At least two arterial blood gas analyses are planned during the surgery.

Exclusion criteria

* No arterial cannulation is necessary or planned for the procedure.

Design outcomes

Primary

Measure	Time frame	Description
Correlate the level of carbon dioxide within arterial blood to inspired and expired oxygen gradient.	At least 2 hours	Compare the levels of carbon dioxide found in the patient's blood to the amounts of carbon dioxide and oxygen in the air that the patient inhales and exhales. If a relationship exists between the levels of carbon dioxide in the blood and the levels of carbon dioxide and oxygen inhaled and exhaled by the patient, anesthesiologists will be able to use this relationship to adjust ventilators during anesthesia without having to take blood from an artery.

Countries

United States

Outcome results