S1119 Peruvian H. Pylori Water Contamination Study

Gastric Cancer and Helicobacter Pylori Infection in Lima, Peru: The Role of Water Contamination

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01512875

Enrollment

107

Registered

2012-01-19

Start date

2011-12-31

Completion date

2013-11-30

Last updated

2015-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Helicobacter Pylori Infection

Keywords

Helicobacter pylori, water contamination, Lima, Peru

Brief summary

The objective of this study is to elucidate the role of drinking water derived from the public source in Lima, Peru and transmission of H. pylori infection using genotypic techniques.

Detailed description

The objective of this study is to detect the presence of Helicobacter Pylori in the drinking water derived from the public network by molecular and genomic techniques in districts of Lima (Brena, Chorrillos, Comas, El Agustino, La Victoria, Lince, Los Olivos, Miraflores, Puente Piedra, Rimac, San Isidro, San Juan de Lurigancho, San Martin de Porres, Villa El Salvador, and Villa Maria del Triunfo) with high and low incidence of gastric carcinoma. The secondary objective of this study is to establish correlations between the findings in water and those of the stomach of patients with symptoms of dyspepsia who live in those districts.

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

21 Years to 70 Years

Healthy volunteers

Inclusion criteria

* adults between the ages of 21-70 years old who have lived for more than 10 years in the Lima districts listed in protocol, * who have a biopsy proven diagnosis of infection by H. pylori. * participants must be in good general condition, mentally competent and able to provide informed consent; * must not show evidence of dehydration or jaundice; * must be willing to complete the patient questionnaires. * participants must not have known allergies to any of the antibiotics used in the study.

Exclusion criteria

* pregnancy

Design outcomes

Primary

Measure	Time frame	Description
Detect H. pylori in public drinking water of Lima Peru	within 1 year of receving last sample	To detect the presence of Helicobacter Pylori (H. pylori) in the drinking water derived from the public network by molecular and genomic techniques in districts of Lima, Peru (districts detailed in protocol).

Secondary

Measure	Time frame	Description
Correlation of H. pylori in water and those of stomachs of patients with symptoms	Within 1 year of receiving last sample	To establish correlations between the findings in water and those of the stomach of patients with symptoms of dyspepsia who live in those districts.

Countries

Peru

Outcome results