POEM- Peroral Endoscopic Myotomy for Esophageal Motility Disorders

POEM a Novel Endoscopic Treatment for Achalasia

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01512719

Acronym

POEM

Enrollment

100

Registered

2012-01-19

Start date

2013-01-31

Completion date

2023-01-31

Last updated

2025-10-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Achalasia

Brief summary

POEM has recently described as an alternative treatment for achalasia in humans. In this procedure the esophageal sphincter is incised through a submucosal tunnel in the esophagus. In this study we aim to perform POEM on achalasia patients.

Interventions

PROCEDUREPOEM

Per Oral Endoscopic Myotomy for achalasia

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 80 Years

Healthy volunteers

Inclusion criteria

* Patients with Achalasia whom are candidates for Heller Myotomy

Exclusion criteria

* Perforation of LES during dilatation * Pregnant women * mentally ill patients

Design outcomes

Primary

Measure	Time frame
Resolution of dysphagia	up to 6 months postoperatively

Countries

Israel

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026