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Improvement of Intentional and Unintentional Non-adherence in the Elderly

Improvement of Intentional and Unintentional Non-adherence in the Elderly. Importance of Pharmaceutical Care, Generic Substitution, Non-prescription Drugs, Herbal Medicine and Dietary Supplements

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT01512238
Enrollment
630
Registered
2012-01-19
Start date
2010-02-28
Completion date
2013-11-30
Last updated
2014-10-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Medication Adherence

Keywords

Medicine adherence, Drug substitution, Herb-drug interaction, Herbal medicine, Dietary supplements, Over-the-counter products, On-line prescription records, Personal electronic medicine profile, Intentional non-adherence, Unintentional non-adherence

Brief summary

The purpose is to study if different factors influence medicine adherence in elderly people. In this study number of generic substitution and use of non-prescription drugs, herbal medicine and dietary supplement is in focus.

Detailed description

The purpose of this study is to describe in the elderly: 1. Association between medicine adherence and number of generic substitution 2. Association between medicine adherence and use of non-prescription drugs, herbal medicine and dietary supplements and interaction between 'prescription drugs' and 'non-prescription drugs, herbal medicine and dietary supplements' 3. Intentional and unintentional non-adherence Some of the data in the present study were originally collected as part of a major research project 'Methods for Improving Compliance with Medicine Intake' (MICMI). The study sample of 945 persons was randomly selected into three groups: two intervention groups and one control group. Interventions were pharmaceutical care and an electronic reminder system. All groups were followed for one year. Data in the present study is from the pharmaceutical care group and the control group, and is descriptive.

Interventions

OTHERPharmaceutical care

Information about medicine, sideeffect, adherence

Sponsors

University of Aarhus
Lead SponsorOTHER

Study design

Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
65 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Aged 65 years or older * Living in their own homes * Without assistance to medicine administration * Living in the Municipality of Aarhus, Denmark * Long-term treatment with \> 4 prescription drugs

Design outcomes

Primary

MeasureTime frame
Medicine adherenceOne year

Secondary

MeasureTime frame
Number of generic substitutionOne year
Use of non-prescription drugs, herbal medicine and dietary supplements and frequency of interaction between 'prescription drugs' and 'non-prescription drugs, herbal medicine and dietary supplements'Actually day
Intentional and unintentional non-adherence association with generic substitution and use of non-prescription drugs, herbal medicine and dietary supplementsOne year

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026