Colonoscopy Failure, Poor Bowel Preparation
Conditions
Keywords
colonoscopy, bowel preparation
Brief summary
Colonoscopy is a basic but important tool to diagnose and treat lesions of the colon. Proper colon cleansing is essential for colonoscopy to be performed with a good quality. Inadequate bowel preparation leads to longer colonoscopic insertion time and patient discomfort, as well as inadequate diagnostic yield of colonic lesions. Frequency of colonoscopy failure due to bad bowel preparation is reported to be 0.3% to 6.5 percent, and the rate increases with liver cirrhosis, constipation, dementia, stroke, or administration of tricyclic antidepressants. In case of colonoscopy failure due to bad bowel preparation, the second colonoscopy can be performed with either adding a colon cleansing solution immediately, or it can be performed after a few days with colon cleansing agent together with prokinetics. These different kinds of bowel preparations after first colonoscopy failure have not been compared.
Interventions
DRUGpolyethylene glycol, Bisacodyl
After failure of first colonoscopy, bowel preparation with polyethylene glycol and bisacodyl one week after
DRUGpolyethylene glycol
Immediately after first colonoscopy failure, polyethylene glycol 2L addition
Sponsors
Asan Medical Center
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
DIAGNOSTIC
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* First colonoscopy failure due to inadequate bowel preparation
Exclusion criteria
* younger than 18 years old * presence of inflammatory bowel disease * pregnant * lactating * refusal
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| second colonoscopy failure due to inadequate bowel preparation (PEG+bisdacodyl group) | one week |
| second colonoscopy failure due to inadequate bowel preparation (PEG group) | within the same day |
Countries
South Korea
Outcome results
None listed