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Transition From Acute to Chronic Pain After Inguinal Hernia, Hysterectomy and Thoracotomy: Analysis of Risk Factors and Association With Genetic Polymorphisms

Transition From Acute to Chronic Pain After Inguinal Hernia, Hysterectomy and Thoracotomy : Analysis of Risk Factors and Association With Genetic Polymorphisms

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT01510496
Enrollment
3979
Registered
2012-01-16
Start date
2009-01-31
Completion date
2014-07-31
Last updated
2015-12-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Postoperative Pain

Keywords

Chronic pain, genetic polymorphisms, postoperative pain

Brief summary

The treatment of postoperative pain continues to be inadequate in the investigators practice setting. Inadequate pain treatment not only contributes to postoperative complications in the short term but can also be a factor that favors the development of chronic postoperative pain and diminishes long-term quality of life. Risk factors that can lead to a transition to chronic pain need to be analyzed.

Interventions

PROCEDUREInguinal herniorraphy.

Inguinal herniorraphy (non laparoscopic).

PROCEDUREHysterectomy.

Hysterectomy: Vaginal and abdominal.

PROCEDUREThoracotomy .

Thoracotomy (non laparoscopic).

Sponsors

Fundacion IMIM
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Patients with given inform consent, aged mor than 18 years, who undergo scheduled surgery of one of the following types: inguinal hernia (men), hysterectomy, thoracotomy (men).

Exclusion criteria

* Patients aged less than 18 years, * Patients requiring reoperation because of surgical complications.

Design outcomes

Primary

MeasureTime frameDescription
Evaluation of chronic postsurgical pain.After 3 and 12 months of surgery.After 3 months a physical examination will take place and after 12 months a follow-up will be reported by phone.

Secondary

MeasureTime frameDescription
Predictive factors of chronic postsurgical pain.After 3 and 12 months of surgery.Preoperative (psychological factors, preoperative pain, pharmacologic treatment) intraoperative (surgical technic, type of anaestesia) and postoperative(posoperative pain, surgical complications and treatment of postoperative pain).

Countries

Spain

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 26, 2026