Topical Lidocaine After Major Arthroscopic Knee Surgery

Topical Lidocaine Patch Does Not Have an Analgesic Effect After Major Arthroscopic Knee Surgery. A Double-blind Place-controlled Randomized Study

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01509729

Enrollment

Registered

2012-01-13

Start date

2011-06-30

Completion date

2012-01-31

Last updated

2015-04-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fracture of Patella, Pain

Keywords

Knee, Arthroscopy, Lidocaine patch, Pain management after knee arthroscopy

Brief summary

Pain after major arthroscopic surgery is dependent on an optimal multimodal analgesic treatment.

Detailed description

Lidocaine is well-known as analgesic treatment on skin and hypodermic veins. Since 1996 it has been documented that topical lidocaine has an analgesic effect 24 hours after surgical treatment. The aim is to determine a possible reduction in pain after knee arthroscopy with topical lidocaine.

Interventions

PROCEDURESham operation

A randomized group of patients received a placebo patch. As a supplement, each patient was given a dose of morphine, as required.

PROCEDUREKnee arthroscopic surgery

A randomized group of patients was given small patches with active 5% lidocaine.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Patients who were planned for reconstruction of anterior crucial ligament, reconstruction of medial patellofemoral ligament and Elmslie-Trillat procedure for patella instability. * Patients with synovectomies and menisci resection lasting more than 25 minutes. * Patients \> 18 years * Acceptance of informed consent

Exclusion criteria

* Patients with rheumatoid arthritis * Patients with a Body Mass index of \> 35 * Patients who can not read and understand Danish * Fertile women who does not use secure contraception

Design outcomes

Primary

Measure	Time frame	Description
Administration of analgesic drugs	24 hours	Time for the first necessary administration of analgesic drugs.

Secondary

Measure	Time frame	Description
Pain management after surgical treatment	24 hours	The intake of necessary analgesic drugs after 6, 12, 18 and 24 hours after surgical treatment. Pain score according to the VAS scale when the patients rest and make movements.

Countries

Denmark

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026