Macular Hole, Trauma
Conditions
Keywords
traumatic macular hole, vitrectomy, observation
Brief summary
The purpose of this study is to compare the anatomical and visual recovery of eyes with traumatic macular hole (TMH) following either early vitrectomy or 6-month observation.
Detailed description
Patients who received vitrectomy immediately after the injury were compared with patients who were observed for six months for spontaneously closure.The closure rate, foveal microstructure, and final visual acuity were analyzed.
Interventions
PROCEDUREvitrectomy surgery
pars plana vitrectomy +internal limiting membrane peeling done immediately after the identification of the macular hole
Sponsors
Peking University Third Hospital
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* closed globe injury * identification of full-thickness macular hole by optical coherence tomography within one month after trauma
Exclusion criteria
* open globe injury * coexistence of idiopathic macular hole * severe opaque in the visual axis caused by the injury(eg. severe cataract, severe vitreous hemorrhage) * combined injuries requiring immediate surgical intervention (eg. lens dislocation, retinal detachment, cyclodialysis) * coexistence of high myopia * coexistence of choroidal rupture or subretinal hemorrhage within the diameter of 400μm from the center of the foveola * coexistence of severe optic nerve injury (no light perception, positive afferent pupillary defect)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| macular hole closure rate | 6 month after injury |
Secondary
| Measure | Time frame |
|---|---|
| central foveal thickness | 6 month after hole closure |
| length of inner-segment outer-segment junction defect | 6 month after hole closure |
| final visual acuity | 6 month after hole closure |
Countries
China
Outcome results
None listed