Assessment of Zinc Absorption From a Phytic Acid Rich Complementary Food

Assessment of Zinc Absorption From a Phytic Acid Rich Complementary Food, Consumed by Young Children Immediately After the Addition of the Enzyme Phytase. A Randomized Single Blind Study

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01506648

Enrollment

Registered

2012-01-10

Start date

2011-01-31

Completion date

2012-10-31

Last updated

2016-11-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bioavailability

Brief summary

Assessment of zinc absorption from a phytic acid rich complementary food, consumed by young children immediately after the addition of the enzyme phytase. A randomized single blind study

Interventions

None listed

Eligibility

Sex/Gender

ALL

Age

12 Months to 24 Months

Healthy volunteers

Yes

Inclusion criteria

1. 12-24 month old 2. Male of female 3. Height and weight between -2.0 SD and +2.0 SD with respect to WHO child growth standards. 4. No mineral and vitamin supplements 2 weeks prior to the study and during the whole duration of the study

Exclusion criteria

1. Body temperature ≥ 37.5°C 2. Hemoglobin ≤ 7g/dL 3. Positive RDT test 4. Any metabolic, gastrointestinal or chronic disease (according to the statement of the subject's parent) known chronic diseases at the gastrointestinal tract) 5. Long term mediation (that may affect zinc metabolism) during the whole study to interact with zinc metabolism (such as kidney diseases or

Design outcomes

Primary

Measure	Time frame	Description
Fractional absorption of zinc	33 days	Fractional absorption of zinc is estimated by using the double isotope tracer ratio technique by administering 67Zn as oral and 70Zn as intravenous stable isotopes.The urinary enrichment with both isotopes is measured in a spot urine sample by inductively coupled plasma mass spectrometry.

Countries

Burkina Faso

Outcome results